54 lines
1.2 KiB
Markdown
54 lines
1.2 KiB
Markdown
---
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name: risk-of-bias
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description: "Assess risk of bias in research studies for systematic reviews. Use when: (1) Conducting systematic reviews, (2) Evaluating study quality, (3) GRADE assessments, (4) Meta-analysis planning."
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allowed-tools: Read, Write
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version: 1.0.0
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---
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# Risk of Bias Assessment Skill
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## Purpose
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Systematically evaluate methodological quality and potential biases in research studies.
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## Tools by Study Design
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**RCTs**: Cochrane Risk of Bias 2 (RoB 2)
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**Non-randomized**: ROBINS-I
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**Diagnostic Studies**: QUADAS-2
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**Prognostic Studies**: QUIPS
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## RoB 2 Domains
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1. **Randomization Process**
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- Adequate sequence generation?
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- Allocation concealment?
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2. **Deviations from Interventions**
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- Blinding effective?
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- Adherence to protocol?
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3. **Missing Outcome Data**
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- Complete data?
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- Appropriate handling?
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4. **Outcome Measurement**
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- Blinded assessment?
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- Validated measures?
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5. **Selective Reporting**
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- All outcomes reported?
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- Pre-registered?
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## Risk Levels
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- **Low**: Minimal bias
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- **Some concerns**: Potential bias
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- **High**: Serious bias likely
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## Integration
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Use with literature-reviewer agent for systematic quality assessment of included studies.
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---
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**Version:** 1.0.0
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