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# Clinical Case Report Template
## Title
[Insert descriptive title that includes "Case Report" or "Case Study" and indicates the clinical focus]
Example: Unusual Presentation of Acute Appendicitis in an Elderly Patient: A Case Report
## Author Information
[Author names, affiliations, ORCID IDs]
**Corresponding Author:**
[Name]
[Email]
[Institution]
## Keywords
[2-5 keywords, preferably MeSH terms]
Example: Appendicitis, Atypical presentation, Elderly, Diagnostic imaging
## Abstract
### Introduction
[What is unique about this case? Why is it worth reporting? 1-2 sentences]
### Patient Concerns
[Primary symptoms and chief complaint]
### Diagnosis
[Final diagnosis, how it was reached]
### Interventions
[Key treatments provided]
### Outcomes
[Clinical outcome and follow-up status]
### Lessons
[Main takeaway messages for clinicians]
**Word count:** [150-250 words]
## Introduction
[Background information - 2-4 paragraphs]
**Paragraph 1:** Background on the condition
- Epidemiology of the condition
- Typical clinical presentation
- Standard diagnostic approach
- Current treatment guidelines
**Paragraph 2:** Why this case is novel
- What makes this case unusual or important
- Gap in medical knowledge addressed
- Literature review showing rarity or uniqueness
- Clinical significance
**Paragraph 3:** Objectives
- Purpose of reporting this case
- Learning points to be highlighted
## Patient Information
**Demographics:**
- Age: [e.g., "A 72-year-old" or "A woman in her 70s"]
- Sex: [Male/Female]
- Ethnicity: [if relevant to case]
- Occupation: [if relevant]
**Medical History:**
- Past medical history: [chronic conditions]
- Past surgical history: [prior surgeries]
- Family history: [relevant family history]
- Social history: [tobacco, alcohol, occupation, living situation]
**Medications:**
- Current medications: [list with doses]
- Allergies: [drug allergies and reactions]
**Presenting Symptoms:**
- Chief complaint: ["Patient's words" or clinical presentation]
- Duration of symptoms
- Severity and characteristics
- Associated symptoms
- Relevant review of systems
## Clinical Findings
**Physical Examination:**
- Vital signs: [T, BP, HR, RR, SpO2]
- General appearance: [overall state]
- Systematic examination by organ system:
- HEENT: [findings]
- Cardiovascular: [findings]
- Respiratory: [findings]
- Abdomen: [findings]
- Neurological: [findings]
- Other relevant systems: [findings]
**Pertinent Negatives:**
[Important negative findings]
## Timeline
| Date/Time | Event |
|-----------|-------|
| [Day -X or Date] | [Initial symptom onset] |
| [Day 0 or Date] | [Presentation to healthcare] |
| [Day 0 or Date] | [Initial evaluation and tests] |
| [Day X or Date] | [Diagnosis confirmed] |
| [Day X or Date] | [Treatment initiated] |
| [Day X or Date] | [Hospital discharge or follow-up] |
| [Month X or Date] | [Long-term follow-up] |
*Note: Use relative days (Day 0, Day 1) or approximate dates (Month 1, Month 3) to protect patient privacy*
## Diagnostic Assessment
### Initial Diagnostic Workup
**Laboratory Tests:**
| Test | Result | Reference Range | Interpretation |
|------|--------|----------------|----------------|
| [Test name] | [Value with units] | [Normal range] | [High/Low/Normal] |
**Imaging Studies:**
- [Modality] ([Date]): [Key findings]
- [Include images if applicable, with labels and arrows pointing to key findings]
**Other Diagnostic Procedures:**
- [Procedure name] ([Date]): [Findings]
### Differential Diagnosis
**Diagnoses Considered:**
1. [Primary differential]
- Supporting evidence:
- Evidence against:
2. [Alternative diagnosis]
- Supporting evidence:
- Evidence against:
3. [Additional differentials as appropriate]
### Diagnostic Challenges
[Describe any difficulties in reaching the diagnosis]
- Atypical presentation
- Misleading initial findings
- Diagnostic delays
- Complex decision-making
### Final Diagnosis
**Confirmed Diagnosis:** [Final diagnosis with ICD-10 code if applicable]
**Diagnostic Reasoning:**
[Explain how diagnosis was reached, key diagnostic features, confirmatory tests]
## Therapeutic Intervention
### Treatment Approach
**Initial Management:**
- [Immediate interventions]
- [Supportive care]
- [Monitoring]
**Definitive Treatment:**
1. **Pharmacological Interventions:**
- [Drug name]: [Dose, route, frequency, duration]
- Indication: [Why prescribed]
- Response: [Patient response to treatment]
2. **Procedural/Surgical Interventions:**
- [Procedure name] performed on [date/day]
- Indication: [Why performed]
- Technique: [Brief description]
- Findings: [Intraoperative or procedural findings]
- Complications: [Any complications or none]
3. **Other Interventions:**
- [Physical therapy, dietary modifications, etc.]
**Alternative Treatments Considered:**
[Other treatment options that were considered and why they were not pursued]
**Changes to Interventions:**
[Any modifications to treatment plan]
- Date of change:
- Reason for change:
- New intervention:
## Follow-up and Outcomes
**Immediate Outcome:**
[Outcome during hospitalization or initial treatment period]
- Clinical response:
- Laboratory or imaging follow-up:
- Complications:
- Length of hospitalization (if applicable):
**Short-term Follow-up:** ([Timeframe, e.g., 1 month])
- Clinical status:
- Follow-up tests:
- Adherence to treatment:
- Any issues or concerns:
**Long-term Follow-up:** ([Timeframe, e.g., 6 months, 1 year])
- Clinical status:
- Recovery or resolution:
- Functional status:
- Quality of life:
- Recurrence or complications:
**Patient-Reported Outcomes:**
[Symptoms, quality of life, patient satisfaction]
## Discussion
**Paragraph 1: Summary and Significance**
[Briefly summarize the case and state its significance]
**Paragraph 2: Literature Review**
[Review similar cases in the literature]
- Number of similar cases reported
- Comparison to this case
- What is novel about this case
- [Cite relevant references]
**Paragraph 3: Clinical Implications**
[What can clinicians learn from this case?]
- Recognition of atypical presentations
- Diagnostic pearls
- Treatment considerations
- When to consider this diagnosis
**Paragraph 4: Pathophysiology or Mechanism (if applicable)**
[Explain underlying mechanism, why this occurred, contributing factors]
**Paragraph 5: Strengths and Limitations**
[Acknowledge limitations of case report]
- Single case report limitations
- Cannot establish causation
- Generalizability concerns
- Strengths of comprehensive evaluation
**Paragraph 6: Future Directions**
[Unanswered questions, areas for future research]
## Learning Points
- [Point 1: Concise, actionable clinical lesson]
- [Point 2: Key diagnostic or treatment pearl]
- [Point 3: When to consider this diagnosis]
- [Point 4: (optional) Additional takeaway]
## Patient Perspective
[Optional but encouraged: Patient's own description of experience, in their own words if possible]
"[Patient quote describing their experience, symptoms, treatment, or outcome]"
[Or narrative description of patient's perspective, impact on quality of life, satisfaction with care]
## Informed Consent
Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal on request.
[OR if patient deceased/unable to consent:]
Written informed consent was obtained from the patient's next of kin for publication of this case report, as the patient was deceased [or unable to provide consent due to...] at the time of manuscript preparation.
## Conflicts of Interest
The authors declare that they have no conflicts of interest.
## Funding
This case report received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.
[OR: This work was supported by [funding source and grant number]]
## Acknowledgments
[Acknowledge contributors who do not meet authorship criteria, providers who cared for patient, etc.]
## References
[Format according to journal requirements - typically AMA, Vancouver, or APA]
1. [First reference - Author(s). Title. Journal. Year;Volume(Issue):Pages.]
2. [Second reference...]
---
## CARE Checklist Completion
Use the CARE checklist to ensure all required elements are included:
- [ ] Title includes "case report"
- [ ] Keywords provided (2-5)
- [ ] Structured/unstructured abstract
- [ ] Introduction with background and novelty
- [ ] Patient demographics (de-identified)
- [ ] Clinical findings
- [ ] Timeline
- [ ] Diagnostic assessment
- [ ] Therapeutic interventions
- [ ] Follow-up and outcomes
- [ ] Discussion with literature review
- [ ] Patient perspective (if possible)
- [ ] Informed consent statement
- [ ] All 18 HIPAA identifiers removed
- [ ] References formatted correctly
- [ ] Figures/tables labeled and referenced
- [ ] Word count within journal limits
---
## De-identification Checklist
Verify all HIPAA identifiers removed:
- [ ] Names (patient, family, providers)
- [ ] Geographic locations smaller than state
- [ ] Exact dates (use year only or relative time)
- [ ] Phone numbers
- [ ] Email addresses
- [ ] Medical record numbers
- [ ] Account numbers
- [ ] License numbers
- [ ] Device serial numbers
- [ ] URLs
- [ ] IP addresses
- [ ] Biometric identifiers
- [ ] Full-face photos (cropped or blurred)
- [ ] Any other identifying information
---
**Notes:**
- Adapt this template to your specific journal's requirements
- Check word count limits (typically 1500-3000 words)
- Follow journal's reference style
- Include institutional review/ethics exemption if applicable
- Consider attaching CARE checklist when submitting